Researchers discover a molecular switch that promotes pancreatic cancer metastasis

More than 62,000 people in the United States will be diagnosed with pancreatic cancer by the end of this year, the vast majority of whom have a fatal and aggressive subtype known as pancreatic ductal carcinoma (PDA). PDA affects more than 90% of patients with pancreatic cancer and the 5-year survival rate is less than … Read more

Cancer risks are passed down through the generations for some families. But there are great hopes for precision medicine

Michelle Brady remembers how much her daughter Addie loved life. the main points: Addie Brady was diagnosed with cancer at ages 9 and 14 Genetic testing revealed that she has a genetic mutation in the TP53 gene, known as the “guardian of the genome.” Researchers are pinning high hopes on what precision medicine can do … Read more

Dr. Eleanor Green: The Deadly Price of Waiting for Medicare | column book

With Christmas approaching, a 48-year-old, but doomed, mother of two arrived at my office in 2018 for medical attention. She said she had a hemorrhage for the past year. But she had no insurance and her budget was limited. So I waited until I got Medicare coverage to see a doctor. My heart broke when … Read more

Study offers a new and unique treatment for AIDS

A new study from Tel Aviv University presents a new and unique treatment for AIDS that could be developed into a vaccine or a one-time treatment for HIV patients. The study examined the engineering of type B white blood cells in a patient’s body to secrete antibodies to HIV in response to the virus. The … Read more

Genetic testing of the most accurate and cost-effective antidepressant

A new study has found that genetic testing to determine the best antidepressant for patients with major depressive disorder (MDD) has the potential to lead to optimal drug selection on the first try and reduce healthcare costs. CYP2D6 and CYP2C19, of the cytochrome P450 family, are involved in the metabolism and disposal of various molecules, … Read more

‘Great optimism’ about complete responses to dMMR rectal cancer

Locally advanced patients rectal cancer Tumors deficient in mismatch repair (dMMR) showed a marked response to treatment with the cell death-1 (PD-1) inhibitor, dostarlimab (Gimberly). So far, the study has included only 12 patients, but all have received a complete clinical response to treatment. They continued to show no signs of cancer (during the 6- … Read more

ctDNA identifies colon cancer patients who can skip chemotherapy

‘Liquid biopsy’ reveals spread of ctDNA after stage II surgery Colon Cancer It helps identify patients who are likely to benefit from adjuvant chemotherapy, and also identifies those who are unlikely to benefit from being allowed to skip this treatment. Results from the Phase II DYNAMIC trial. Commented first author Jane Tai, MD, of the … Read more

New genetic trial shrinks hard-to-treat cancer

In a new experiment, a woman with advanced pancreatic cancer saw her tumors shrink dramatically after researchers in Oregon charged her immune cells, highlighting a potential new way to one day treat a variety of cancers. Kathy Wilkes has not been cured but said the rest of the cancer has shown no sign of growth … Read more

What’s wrong with Vladimir Putin? – Politico

Click play to listen to this article Never believe in anything in politics until it has been officially rejected. Even then, when it comes to Vladimir Putin’s health, you can still be forgiven for being at a loss as to what to believe, given the frenzy of baffling speculation about whether something was wrong with … Read more